Are you passionate about solving complex scientific problems at the intersection of molecular science and the latest digital technology? Do you want to be at the cutting edge of molecular diagnostics, where data, artificial intelligence, and precision analytics converge to shape the future of healthcare and research? If so, the Institute for Digital Molecular Analytics and Science (IDMxS) offers several exciting PhD research projects that push the boundaries of innovation in this field.
At IDMxS, based at Nanyang Technological University (NTU) and supported by the National University of Singapore (NUS), you’ll be part of a vibrant research community. You’ll engage in projects that address global challenges, ranging from chronic diseases to the rapid detection of emerging pathogens.
Below are just a few of the exciting PhD projects we offer. Please note that additional opportunities may be available, and we encourage prospective students to contact individual principal investigators for further information.
Featured PhD Projects
Synthesis and Characterization of Conjugated Oligoelectrolytes for Bio-imaging Applications
Supervisor: Prof Guillermo Bazan
This project focuses on the design and synthesis of novel conjugated oligoelectrolytes (COEs) for advanced bio-imaging applications. COEs offer significant potential as molecular platforms for single-molecule detection techniques, such as fluorescence lifetime imaging microscopy (FLIM), which could identify biomarkers linked to ageing and antibiotic-resistant bacteria.
For more information, contact: guillermo.bazan@ntu.edu.sg
Synthesis of Novel Conjugated Oligoelectrolytes for Combatting Antimicrobial Resistance
Supervisor: Prof Guillermo Bazan
This project addresses the global threat of antimicrobial resistance (AMR) by developing novel COEs that disrupt bacterial membranes, offering a fresh approach to antibiotic development. COEs are uniquely positioned to provide new lead compounds for treating difficult infections, including non-tuberculous mycobacteria.
For more information, contact: guillermo.bazan@ntu.edu.sg
Information and Decision Theory in Biosensing and Diagnostics
Supervisor: Asst Prof Matthew Foreman
This project takes an innovative approach to biosensing by analysing optical assays from an information theory standpoint. Using decision theory and computational imaging techniques, this research will develop diagnostic tools with enhanced sensitivity for real-time detection of pathogens and disease biomarkers.
For more information, contact: matthew.foreman@ntu.edu.sg
Multiplexed Detection with AI-Driven Error Tolerance
Supervisor: Assoc Prof Wang Lipo
AI-driven detection systems are at the heart of this project, which aims to enhance the accuracy and error tolerance of multiplexed biological and chemical detection in noisy environments. Applications of this research include environmental monitoring, healthcare diagnostics, and food safety.
For more information, contact: ELPWang@ntu.edu.sg
Machine-learning Based Design of Biomolecular Condensates for Sensing
Supervisor: Assoc Prof Miao Yansong
By combining machine learning with protein engineering, this project focuses on designing biomolecular condensates for sensing disease markers with exceptional accuracy. These novel sensing platforms have transformative potential in diagnosing immune-related diseases and enhancing agrifood security.
For more information, contact: yansongm@ntu.edu.sg
Multiplex Imaging for Sensing Biochemical Reactions from Single Molecular to Microenvironmental Level
Supervisor: Assoc Prof Miao Yansong
This project is developing advanced imaging platforms capable of real-time biochemical sensing at both single-molecule and multicellular levels. These platforms aim to provide detailed insights into biomolecular activities, aiding in the study of complex diseases and advancing biomedical applications.
For more information, contact: yansongm@ntu.edu.sg
Why Join IDMxS?
At IDMxS, you’ll become part of an innovative, interdisciplinary research environment that combines expertise in molecular analytics, sensor technology, and advanced data sciences. You’ll have access to state-of-the-art laboratories, computational tools, and an international network of collaborators. As a PhD student, you’ll be empowered to lead cutting-edge research projects and drive breakthroughs that make a real-world impact.
Apply Today!
For more information on making an application, visit our PhD Programme page.
Interested candidates are also encouraged to reach out to the relevant supervisors listed above for further details. To enquire about additional PhD opportunities, please contact our IDMxS Principal Investigators.
Join IDMxS and embark on a journey where science meets innovation to solve tomorrow’s challenges today!